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406 Ventures Management, LLC

SEC exempt reporting adviser (venture capital exemption).

HQ
MA

406 Ventures Management, LLC is a venture firm that backs early-stage companies in healthcare, data and AI, and cybersecurity, focusing on industries it knows well. Its portfolio includes Vitalize, Teal Health, Abacus Insights, Absurd, Big Health, Bobsled, Mindgard, and Traversal. The team includes Liam Donohue, Co-Founder and Managing Partner, along with several partners, a venture partner, and a principal.

01 · Says / Does

TagSaysDoesHistorically (to 2020)
StagesSeed, Series ASeries ASeries A, Growth, Series B
SectorsAI infra, AI applications, Cybersecurity, Data analytics, HealthtechHealthtechEnterprise SaaS, Cybersecurity, Healthtech, Data analytics, Devtools
RegionsUSNot enough dated dealsMA, NY

Says: what the firm's funds state. Does: from 2 dated deals in the last 24 months.

Historical focus (through 2020), derived from historical deal data.

YearDealsTop sectors
20076Cybersecurity, Enterprise SaaS
200810Devtools, Enterprise SaaS, Cybersecurity
20094Biotech, Climate hardware, Cybersecurity
20104Data analytics, Enterprise SaaS, Cybersecurity
20115Enterprise SaaS, Devtools, Media
20129Enterprise SaaS, Cybersecurity, Data analytics
20137Cybersecurity, Enterprise SaaS, Healthtech
201412Enterprise SaaS, Cybersecurity, AI applications
201515Enterprise SaaS, Data analytics, Cybersecurity
201615Cybersecurity, Data analytics, Enterprise SaaS
201710Data analytics, Healthtech, Cybersecurity
201813Healthtech, Medical devices, AI applications
20199Enterprise SaaS, Healthtech, Cybersecurity
20206Healthtech, Data analytics, AI applications

Stage mix over time

2010 Growth: 3102011 Series B: 12011 Growth: 2112012 Seed: 22012 Series A: 22012 Series B: 12012 Growth: 3122013 Seed: 12013 Series A: 52013 Series B: 1132014 Seed: 12014 Series A: 62014 Series B: 22014 Growth: 3142015 Seed: 12015 Series A: 62015 Series B: 42015 Growth: 4152016 Seed: 42016 Series A: 32016 Series B: 52016 Growth: 3162017 Series A: 32017 Series B: 22017 Growth: 5172018 Seed: 22018 Series A: 52018 Series B: 22018 Growth: 3182019 Series A: 32019 Series B: 22019 Growth: 4192020 Series A: 22020 Series B: 12020 Growth: 220212223242025 Series A: 3252026 Series A: 12026 Growth: 126
  • Pre-seed
  • Seed
  • Series A
  • Series B
  • Growth
Share of rounds by stage, per year. Striped years have fewer than 3 rounds.Historical focus (through 2020), derived from historical deal data.From public announcements.
Rounds by stage and year
YearPre-seedSeedSeries ASeries BGrowth
201000003
201100012
201202213
201301510
201401623
201501644
201604353
201700325
201802523
201900324
202000212
202100000
202200000
202300000
202400000
202500300
202600101

02 · Fund history

FundYearSizeStatus
Point 406 AI, LLC

406 Ventures backs early-stage companies at the seed and Series A stages in healthcare, data and AI, and cybersecurity. It focuses on industries it knows well and partners closely with founders beyond capital. Inferred from the firm's website

2024$5.48M (Form D)Open, writing first checks
Point 406 Ventures V, L.P.

406 Ventures backs early-stage companies at the seed and Series A stages in healthcare, data and AI, and cybersecurity. It focuses on industries it knows well and partners closely with founders beyond capital. Inferred from the firm's website

2022$244.87M to $325M (Form D)Late investment period
Wrangler Too, LLC

406 Ventures backs early-stage companies at the seed and Series A stages in healthcare, data and AI, and cybersecurity. It focuses on industries it knows well and partners closely with founders beyond capital. Inferred from the firm's website

2021$5.09M (Form D)Late investment period
MinTCo, LLC2020$5.4M (Form D)Follow-ons only
Co-napsis, LLC2020$7.55M to $7.65M (Form D and SEC adviser filing)Follow-ons only

03 · People across funds

04 · Recent deals

  • Oct 6, 2026VitalizeSeries AFirmsource
  • Sep 22, 2026Teal HealthStage unknownFirmsource

05 · Latest from the firm

06 · Sources

  1. HTTP://WWW.406VENTURES.COM
  2. https://www.406ventures.com/contact/
  3. https://www.406ventures.com/people/
  4. https://www.406ventures.com/companies
  5. https://www.406ventures.com/news/vitalize-raises-31m-series-a-to-bring-air-traffic-control-to-healthcare/
  6. https://www.406ventures.com/our-focus/
  7. https://www.406ventures.com/news/406-ventures-marks-20-years-with-100th-investment-and-promotion-of-kathryn-taylor-reddy/

Fund dates and sizes are from SEC Form D filings.

Last verified: Oct 28, 2026