Signet Healthcare Management LLC
SEC exempt reporting adviser (venture capital exemption).
- HQ
- NY
Signet Healthcare Management LLC is a healthcare growth investor focused on commercial-stage companies, mainly in pharmaceuticals and medical devices. Its portfolio includes NorthX Biologics, PainTEQ, and Primrose Bio, Inc., and it also lists Chr. Olesen Synthesis, RK Pharma, Curida, and Paragonix Technologies. The firm has a team of managing directors, vice presidents, and associates.
New fund likely raising soon
The firm's newest fund is 4 to 7 years past its first sale and no newer Form D has been filed.
01 · Says / Does
| Tag | Says | Does | Historically (to 2020) |
|---|---|---|---|
| Stages | Growth | Not enough dated deals | Growth, Series B, Series A |
| Sectors | Biotech, Medical devices | Not enough dated deals | Biotech, Healthtech, Manufacturing |
| Regions | Global | Not enough dated deals | CA |
Says: what the firm's funds state. Does: from 3 dated deals in the last 24 months.
Historical focus (through 2020), derived from historical deal data.
| Year | Deals | Top sectors |
|---|---|---|
| 2004 | 1 | Biotech, Manufacturing |
| 2007 | 2 | Biotech, Manufacturing |
| 2008 | 2 | Healthtech, Biotech, Medical devices |
| 2009 | 1 | Biotech, Healthtech |
| 2010 | 1 | Biotech, Life sciences and research tools |
| 2011 | 1 | Biotech |
| 2014 | 2 | Biotech, Healthtech, Medical devices |
| 2015 | 2 | Biotech, Healthtech |
| 2017 | 1 | Biotech, Life sciences and research tools |
| 2018 | 2 | Healthtech, Manufacturing, Biotech |
Stage mix over time
- Pre-seed
- Seed
- Series A
- Series B
- Growth
| Year | Pre-seed | Seed | Series A | Series B | Growth |
|---|---|---|---|---|---|
| 2010 | 0 | 0 | 0 | 1 | 0 |
| 2011 | 0 | 0 | 0 | 0 | 1 |
| 2012 | 0 | 0 | 0 | 0 | 0 |
| 2013 | 0 | 0 | 0 | 0 | 0 |
| 2014 | 0 | 0 | 0 | 1 | 0 |
| 2015 | 0 | 0 | 1 | 0 | 0 |
| 2016 | 0 | 0 | 0 | 0 | 0 |
| 2017 | 0 | 0 | 0 | 0 | 1 |
| 2018 | 0 | 0 | 0 | 1 | 0 |
| 2019 | 0 | 0 | 0 | 0 | 0 |
| 2020 | 0 | 0 | 0 | 0 | 0 |
| 2021 | 0 | 0 | 0 | 0 | 0 |
| 2022 | 0 | 0 | 0 | 0 | 1 |
| 2023 | 0 | 0 | 0 | 1 | 0 |
| 2024 | 0 | 0 | 0 | 0 | 1 |
| 2025 | 0 | 0 | 0 | 0 | 1 |
| 2026 | 0 | 0 | 0 | 0 | 0 |
02 · Fund history
| Fund | Year | Size | Status |
|---|---|---|---|
| Signet Healthcare Partners QP Partnership V, LP | 2022 | $191.1M to $300M (Form D) | Late investment period |
03 · People across funds
- Ashley Friedman, Manager of the Investment Adviser
Signet Healthcare Partners QP Partnership V, LP (Named on Form D)
- James Gale, Chief Investment Officer of the Investment Adviser
Signet Healthcare Partners QP Partnership V, LP (Named on Form D)
- LLC Signet Healthcare GP V,, "General Partner of the GP of the Issuers (the ""Top GP"")"
Signet Healthcare Partners QP Partnership V, LP (Named on Form D)
- LP Signet Healthcare GP V,, "General Partner of the Issuers (the ""GP"")"
Signet Healthcare Partners QP Partnership V, LP (Named on Form D)
- Nikhil Puri, Manager of the Investment Adviser
Signet Healthcare Partners QP Partnership V, LP (Named on Form D)
- Audrey Liu, Associate
- Emad Piracha, Vice President
- Vladimir Walko, Business Development Officer
04 · Recent deals
05 · Latest from the firm
- InvestmentPrimrose Bio Raises Significant Growth Capital Investment Led by Signet Healthcare Partners — Signet Healthcare PartnersSep 22, 2026
- InvestmentPainTEQ Secures Majority Growth Recapitalization Co-Led by Signet Healthcare Partners & Windham Capital Partners — Signet Healthcare PartnersAug 27, 2025
- InvestmentNorthX Biologics secures significant growth investment from Signet Healthcare Partners — Signet Healthcare PartnersMay 14, 2025
06 · Sources
- HTTP://SIGNETHEALTHCAREPARTNERS.COM
- http://www.signethealthcarepartners.com/contact
- http://www.signethealthcarepartners.com/news/2025/8/27/painteq-secures-majority-growth-recapitalization-co-led-by-signet-healthcare-partners-amp-windham-capital-partners
- http://www.signethealthcarepartners.com/team
- http://www.signethealthcarepartners.com/news/2025/5/14/northx-biologics-secures-significant-growth-investment-from-signet-healthcare-partners
- http://www.signethealthcarepartners.com/news
- http://www.signethealthcarepartners.com/about
- http://www.signethealthcarepartners.com/news/2026/9/22/primrose-bio-raises-significant-growth-capital-investment-led-by-signet-healthcare-partners
Fund dates and sizes are from SEC Form D filings.
Last verified: Oct 25, 2026